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Symbol
Name
ID
Cd8a
CD8 subunit alpha
MGI:88346
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
increased CD8-positive, alpha-beta memory T cell proliferation
abnormal CD4-positive T cell differentiation
abnormal CD8-positive, alpha-beta T cell differentiation
decreased CD8-positive, alpha-beta T cell number
absent CD8-positive, alpha-beta T cells
abnormal CD8-positive, alpha beta T cell morphology
abnormal CD8-positive, alpha-beta T cell physiology
abnormal cytotoxic T cell physiology
increased susceptibility to Herpesvirales infection
increased susceptibility to Picornaviridae infection
abnormal response to transplant
Availability Mouse Genotype
Cd8am1Btlr/Cd8am1Btlr
Cd8am2Btlr/Cd8am2Btlr
Cd8atm1.1(cre)Koni/Cd8atm1.1(cre)Koni
Cd8atm1.1Kio/Cd8atm1.1Kio
Cd8atm1.1Litt/Cd8atm1.1Litt
Cd8atm1.1Welm/Cd8atm1.1Welm *
Cd8atm1Mak/Cd8atm1Mak *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory